Lakatos P, Hegedűs Cs, Ayestarán NS, Juarranz Á, Kövér EK, Szabó É, Virág L: The PARP inhibiton PJ-34 sensitizes cells to UVA-induced phototoxicity by a PARP independent mechanism. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 79, 31-40 (2016)

Géhl Zs, Bakondi E, Resch MD, Hegedűs Cs, Kovács K, Lakatos P, Szabó A, Nagy Z, Virág L: Diabetes-induced oxidative stress in the vitreous humor. Redox Biology 9, 100-103 (2016)

Rodriguez-Vargas JM, Rodriguez MI, Majuelos-Melguizo J, Garcia-Diaz A, Gonzalez-Flores A, Lopez-Rivas A, Virág L, Illuzzi G, Schreiber V, Dantzer F, Oliver FJ: Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export. Cell Death and Differentiation 1-12 (2016)

Brunyánszki A, Szczesny B, Virág L, Szabó C: Mitochondrial poly(ADP-ribose) polymerase: the Wizard of Oz at work. Free Radical Biology and Medicine 100, 257-270 (2016)

Virág L: A védőenzimi is árthat - A sokarcú sejthalál és a PARP1 karrierje. Élet és Tudomány 25, 777-779 (2016)

Dedinszki D, Sipos A, Kiss A, Bátori R, Kónya Z, Virág L, Erdődi F, Lontay B: Protein phosphatase-1 is involved in the maintenance of normal homeostasis and in UVA irradiation-induced pathological alterations in HaCaT cells and in mouse skin. Biochimica et Biophysica Acta - Molecular Basis of Disease 1852, 22-33 (2015)

Kiss B, Szántó M, Szklenár M, Brunyánszki A, Marosvölgyi T, Sárosi E, Remenyik É, Gergely P, Virág L, Decsi T, Rühl R, Bai P: Poly(ADP) ribose polymerase-1 ablation alters eicosanoid and docosanoid signaling and metabolism in a murine model of contact hypersensitivity. Molecular Medicine Reports 11, 2861-2867 (2015)

Hegedűs Cs, Robaszkiewicz A, Lakatos P, Szabó É, Virág L.: Poly(ADP-ribose) in the bone: from oxidative stress signal to structural element. Free Radical Biology and Medicine 82, 179-186 (2015)

Gegely Sz, Hegedűs Cs, Lakatos P, Kovács K, Gáspár R, Csont T, Virág L: High throught screening identifies a novel compund protecting cardiomyocytes from doxorubicin-induced damage. Oxidative Medicine and Cellular Longevity 2015, 1-5 (2015)

Szántó M, Brunyánszki A, Márton J, Vámosi G, Nagy L,  Fodor T, Kiss B, Virág L, Gergely P, Bai P. Deletion of PARP-2 induces hepatic cholesterol accumulation and decrease in HDL levels. Biochim. Biophys. Acta (Molecular Basic of Disease) 1842, 594-602 (2014)

Csóka B, Koscsó B, Törő G, Kókai E, Virág L, Németh ZH, Pacher P, Bai P, Haskó G: A2B adenosine receptors prevent adipose tissue inflammation and insulin resistance by maintaining alternative macrophage activation. Diabetes 63(3), 850-866 (2014)

Hegedűs Cs, Virág L: Inputs and outputs of poly(ADP-ribosyl)ation: relevance to oxidative stress. Redox Biology 2, 978-982 (2014)

El-Hamoy T, Hegedűs Cs, Lakatos P, Kovács K, bai P, El-Ghazaly MA, El-Denshary ES, Szabó É, Virág L: Activation of poly(ADP-ribose) polymerase-1 delays wound healing by regulating keratinocyte migration and production of inflammatory mediators. Molecular Medicine 20, 363-371 (2014)

Robeszkiewicz A, Valkó Zs, Kovács K, Hegedűs Cs, Bakondi E, Bai P, Virág L: The role of p83 signaling and poly(ADP-ribosyl)ation-induced metabolic collapse in the osteogenic differentiationi-coupled cell. Free Radical Biology and Medicine 76, 69-79 (2014)

Nagy L, Docsa T, Szántó M, Brunyánszki A, Hegedűs C, Márton J, Kónya B, Virág L, Somsák L, Gergely P, Bai P.: Glycogen Phosphorylase Inhibitor N-(3,5-Dimethyl-Benzoyl)-N'-(β-D-Glucopyranosyl)Urea Improves Glucose Tolerance under Normoglycemic and Diabetic Conditions and Rearranges Hepatic Metabolism. PLoS One. 2013 Jul 25;8(7):e69420. (2013)

Koscsó B, Csóka B, Kókai E, Németh ZH, Pacher P, Virág L, Leibovich SJ, Haskó G.: Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages. J Leukoc Biol. 94(6): 1309-1315 (2013)

Oit-Wiscombe I, Virag L, Soomets U, Altraja A.: Increased DNA Damage in Progression Of COPD: A Response By Poly(ADP-Ribose) Polymerase-1. PLoS One. 2013 Jul 24;8(7):e70333, 8 p. (2013)

Virág L.: 50Years of poly(ADP-ribosyl)ation. Mol Aspects Med. 34(6): 1043-1045 (2013),  doi:pii: S0098-2997(13)00039-3. 10.1016/j.mam.2013.05.002.

Erdélyi K, Pacher P, Virág L, Szabó C.: Role of poly(ADP-ribosyl)ation in a 'two-hit' model of hypoxia and oxidative stress in human A549 epithelial cells in vitro. Int J Mol Med. 32(2): 339-346 (2013)  doi: 10.3892/ijmm.2013.1397.

Hegedűs C, Lakatos P, Kiss-Szikszai A, Patonay T, Gergely S, Gregus A, Bai P, Haskó G, Szabó É, Virág L : Cytoprotective dibenzoylmethane derivatives protect cells from oxidative stress-induced necrotic cell death. Pharmacol Res. 2013Jun;72:25-34. doi: 10.1016/j.phrs.2013.03.002. (2013)

Palicz Z, Jenes A, Gáll T, Miszti-Blasius K, Kollár S, Kovács I, Emri M, Márián T, Leiter E, Pócsi I, Csősz E, Kalló G, Hegedűs C, Virág L, Csernoch L, Szentesi P.: In vivo application of a small molecular weight antifungal protein of Penicillium chrysogenum (PAF). Toxicol Appl Pharmacol. 2013 May 15;269(1):8-16. (2013)

Virág L, Robaszkiewicz A, Vargas JM, Javier Oliver F.: Poly(ADP-ribose) signaling in cell death. Mol Aspects Med. 34(6): 1153-1167 (2013) doi:pii: S0098-2997(13)00008-3. 10.1016/j.mam.2013.01.007.

Bürkle A, Virág L.: Poly(ADP-ribose): Paradigms and paradoxes. Mol Aspects Med.  34(6), 1046-1065 (2013). doi:pii: S0098-2997(12)00157-4. 10.1016/j.mam.2012.12.010.

Lakatos P, Szabó E, Hegedűs C, Haskó G, Gergely P, Bai P, Virág L:. 3-Aminobenzamide protects primary human keratinocytes from UV-induced cell death by a poly(ADP-ribosyl)ation independent mechanism. Biochim Biophys Acta. 2013 Mar;1833(3):743-51. (2013)

Bai P, Virág L.: Role of poly(ADP-ribose) polymerases in the regulation of inflammatory processes. FEBS Lett. 2012 Nov 2;586(21):3771-7. (2012)

Kovács K, Erdélyi K, Hegedűs C, Lakatos P, Regdon Z, Bai P, Haskó G, Szabó E, Virág L.:  Poly(ADP-ribosyl)ation is a survival mechanism in cigarette smoke-induced and hydrogen peroxide-mediated cell death. Free Radic Biol Med. 2012 Nov 1;53(9):1680-8. (2012)

Robaszkiewicz A, Erdélyi K, Kovács K, Kovács I, Bai P, Rajnavölgyi E, Virág L.: Hydrogen peroxide-induced poly(ADP-ribosyl)ation regulates osteogenic differentiation-associated cell death. Free Radic Biol Med. 2012 Oct 15;53(8):1552-64. (2012)

Szántó M, Brunyánszki A, Kiss B, Nagy L, Gergely P, Virág L, Bai P.: Poly(ADP-ribose) polymerase-2: emerging transcriptional roles of a DNA-repair protein. Cell Mol Life Sci. 2012 Dec;69(24):4079-92. (2012)

Géhl Zs*, Bai P*, Bodnár E, Emri G, Remenyik É, Németh J, Gergely P, Virág L, Szabó É: Poly(ADP-ribose) in the skin and in malignant melanomas. HISTOLOGY AND HISTOPATHOLOGY 2012 May;27(5):651-9. (2012)

Koscsó B, Csóka B, Selmeczy Zs, Himer L, Pacher P, Virág L, Haskó G: Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process. JOURNAL OF IMMUNOLOGY 188: pp. 445-453. (2012)

Szántó M*, Rutkai I*, Hegedűs Cs, Czikora Á, Rózsahegyi M, Kiss B, Virág L, Gergely P, Tóth A, Bai P: Poly(ADP-ribose) polymerase-2 depletion reduces doxorubicin-induced damage through SIRT1 induction. CARDIOVASCULAR RESEARCH 92:(3) pp. 430-438. (2011)

Szabó É, Kovács I, Grune T, Haczku A, Virág L: PARP-1: a new player in the asthma field? ALLERGY 66: pp. 811-814. (2011)

Haskó Gy, Csóka B, Koscsó B, Chandra R, Pacher P, Thompson LF, Deitch EA, Spolarics Z, Virág L, Gergely P, Rolandelli RH, Németh ZH: Ecto-5’-nucleotidase (CD73) decreases mortality and organ injury in sepsis. JOURNAL OF IMMUNOLOGY 187: pp. 4256-4267. (2011)

 

 

Animation

User login